I can confirm error Forefront TMG detected changes in Microsoft Exchange Server or Microsoft Forefront Protection configuration, and reapplied the e-mail policy configuration on server 'TMG' when products like Forefront TMG, Forefront Protection Manager for Exchange and Exchange Edge server were installed on the same server.
I see this error in Application Log every hour, when Exhange Hub Transport server initiates EdgeSync.
Mail flows seems okay, except I have this annoying error in the log.
MCP, MCSA 2003, MCSE 2003